Abdominal distension is like a drum, it turned out to be caused by "a little red"


Recently, Nanjing Gulou Hospital received a visit from Aunt Zhong from Fujian. She began experiencing abdominal distension and discomfort more than a month ago, and her abdomen was getting larger and larger. During the diagnosis and treatment, the doctor discovered that Aunt Zhong boiled water with a plant called "a little red" to drink. In response, doctors remind that some plants that have been soaked in water for a long time and consumed in large quantities not only fail to maintain health, but also pose a serious threat to health and even endanger life. A little red tea soaked in "herbal tea" caused bloating like a drum at the beginning of the disease. Aunt Zhong sought medical attention from the local hospital's interventional department. After examination, it was found that there was liver enlargement, abnormal liver function, and a large amount of ascites. During hospitalization, further interventional examinations ruled out the causes of "Budd Chiari syndrome" and "liver cirrhosis", but the diagnosis was delayed. Aunt Zhong searched online and learned that Professor Zhuge Yuzheng's team from the Department of Gastroenterology at Nanjing Gulou Hospital has rich experience in treating her type of disease. Therefore, she was referred to Gulou Hospital for further diagnosis and treatment. After questioning by the medical team, it was learned that Aunt Zhong has been troubled by chronic pharyngitis for many years. Before the 2023 Spring Festival, she returned to her hometown in Fujian and heard from relatives that "a little red" can clear heat, detoxify, anti-inflammatory and analgesic, and has a good therapeutic effect on chronic pharyngitis. So she found a "little red" root from her neighbor's house, sliced and boiled water, and drank it as "herbal tea" every day. After drinking it for a month, she began to suffer from abdominal distension, fatigue and other discomfort symptoms. The inspection found that transaminase abnormalities, jaundice, ascites. Combined with imaging examination, Aunt Zhong's liver showed typical "map like" changes. Based on experience, Zhuge Yuzheng and his team quickly diagnosed that Aunt Zhong's liver sinus obstruction syndrome was caused by excessive consumption of a little red. After the surgery, Aunt Zhong's abdominal distension improved significantly and her liver function basically returned to normal. The so-called hepatic sinus obstruction syndrome is a drug-induced damage to the endothelial cells of the hepatic sinuses/venules, leading to acute or subacute liver injury and acute portal hypertension in patients. It has medicinal properties and toxicity, so it is important to be cautious when eating. "A little red" is very common in rural areas, and it is an annual herbaceous plant in the composite family. Traditional Chinese medicine believes that Yidian has a flat red nature, bitter taste, slight pungency, cooling blood and detoxification, and plays a good medicinal role in treating urinary system infections, pharyngitis, and ulcers. However, although 'a little red' can clear heat and detoxify, it is also truly toxic. The main chemical components of "Yidianhong" are alkaloids, flavonoids, volatile oils, and other compounds, including toxic alkaloids such as pyrrolizidine, which are the main culprits causing liver damage and resulting in a large amount of ascites. When it reacts with cellular metabolites, even DNA and proteins, it has strong cytotoxicity and even carries the risk of cancer. It should be noted that the purple grass family, the Senecio and Zelan families of the Compositae family, and the pig dung bean genus of the Leguminosae family are common distribution plants of pyrrolizidine alkaloids. The previously frequently reported poisoning of Sophora notoginseng is also a similar situation. Experts remind you not to consume the plants mentioned in these taxonomic groups casually. The reporter learned that the Gastroenterology Department of Nanjing Gulou Hospital receives dozens of patients with hepatic sinus obstruction syndrome caused by ingestion of various plants every year, and has developed the world's first expert consensus on the diagnosis and treatment of hepatic sinus obstruction syndrome. Professor Zhuge Yuzheng's team has found through years of research that about 60% to 70% of liver sinus obstruction

Edit:qihang Responsible editor:xinglan


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