*** In the context of the construction of Guangdong Hong Kong Macao Great Bay area, Guangzhou resolutely implements the decision-making and deployment of the CPC Central Committee and the work requirements of the provincial Party committee and the provincial government, grasps the major historical opportunities such as the construction of "two districts", the linkage of "two cities" and the construction of Hengqin and Qianhai cooperation zones, and follows the whole chain innovative development path of "scientific discovery, technological development, industrial development, talent support and ecological optimization", Accelerate the construction of a strong scientific and technological innovation city with global influence and jointly build an international scientific and technological innovation center in Dawan District, Guangdong, Hong Kong and Macao, so as to promote the development of scientific and technological innovation from the following innovation stage of "industry driving science and technology" to the positive innovation stage of "science leading industry". As a national central city and provincial capital city, Guangzhou has a profound historical and cultural heritage, strong comprehensive economic strength and an open, inclusive and innovative city image. In recent years, with Zhongxin Guangzhou Knowledge City and Nansha Science City as the poles, build a scientific and technological innovation axis linking the key nodes of the city, and improve the innovation level of "one district, three cities and multiple nodes". Build a solid foundation and build a first-class scientific Highland A set of data highlights the improvement of innovation level in Guangzhou. The global innovation index of Guangzhou Shenzhen Hong Kong Innovation Cluster ranked second for two consecutive years. The ranking of "natural index - scientific research city" jumped from Guangzhou to 14th in the world, and the domestic ranking rose from 9th to 4th in 2015. Basic research investment accounts for 14.2% of RD funds, ranking second in China and close to the level of advanced countries in the world. Establish and improve the funding system for basic research and deepen cooperation with the National Natural Science Foundation of China. In 2020, it won 3188 projects approved by the National Natural Science Foundation of China, ranking third in China. A number of achievements show Guangzhou's scientific and technological hard core strength. Major original and cutting-edge achievements continue to emerge. In 2020, many achievements such as trial production of combustible ice and supercomputing application of Tianhe 2 were selected into China's top ten scientific and technological progress, and trial production of combustible ice created two world records of "total gas production and average daily gas production". In 2019, two achievements of Sun Yat sen University were selected into the "top ten scientific and technological progress of Chinese universities", which is the largest number of universities in China. In 2018, "pushing forward the history of human life on the Loess Plateau to 2.12 million years ago" was selected as one of the top ten scientific advances in China. Our city won 22 national science and technology awards in 2020, accounting for 61% of the province. Zhong Nanshan respiratory disease prevention and control innovation team won the only innovation team award in China. Academician Zhong Nanshan, as the main person completing the project of "prevention and control strategy and clinical diagnosis and treatment of new coronavirus infection", won the special prize for scientific and technological progress of Guangdong Province in 2020, and song Erwei, academician of the Chinese Academy of Sciences and President of Sun Yat Sen Memorial Hospital of sun Yat sen University, won the outstanding contribution award. One system to consolidate the foundation of basic research in Guangzhou. Build a "2 + 2 + n" guided by the two national aircraft carrier platforms of Guangzhou laboratory and the national technological innovation center of Guangdong, Hong Kong and Macao, with two major scientific and technological infrastructure of human cell lineage and cold spring ecosystem as the backbone, and based on major platforms such as the national new display technology innovation center, four provincial laboratories and more than 10 high-level innovation research institutes Scientific and technological innovation platform system. Guangzhou laboratory: focusing on the national strategic objectives and major needs, build a strategic scientific and technological force in the respiratory field, tackle major basic theoretical problems and key core technologies, and build a large comprehensive research base and original innovation source. Guangdong, Hong Kong and Macao Dawan District National Technological Innovation Center: focusing on the major mission of building an international scientific and technological innovation center in Guangdong, Hong Kong and Macao Dawan District, build a hub platform of regional industrial technological innovation system with global vision and international leadership, take key technology R & D as the core mission, build a strategic node of the national technological innovation system and support the "four beams and eight pillars" of the national regional innovation system. Large scientific research facilities of human cell lineage: focus on major respiratory diseases, immune cells and other research fields, build a national human cell lineage resource database and digital model, and lay a solid foundation for the scientific research, technology and industrial development of biomedicine in Dawan district. Cold spring ecosystem research device: facing the major national needs, the construction of "in-situ intelligent financing research system + simulation experiment system" can provide a scientific research tool for understanding the deep-sea cold spring ecosystem and ensuring the green development and utilization of combustible ice. First class ecology shapes the atmosphere of scientific and technological innovation in Guangzhou. "Success depends on talent, and industry depends on talent". The cause of innovation calls for innovative talents. Guangzhou adheres to the global vision and international standards, and sincerely attracts talents with the insight of knowing talents, the sincerity of loving talents, the courage of using talents and the magnanimity of accepting talents. Many top scientists such as Zhong Nanshan, Xu Tao and academician Zhang Luo were gathered. Top scientists such as Zhao Yuliang, Shi Yigong, Wang Xiaodong and ye Tianchun came to Guangzhou to innovate and start businesses. More than 120 academicians of the two academies worked in Guangzhou and more than 12000 talent green cards were issued. Among them, four provincial laboratories such as Biological Island and southern marine science and engineering have gathered nearly 40 academicians and 270 high-level talent teams. As a national platform for talent introduction, the 22nd Shanghai International Trade Fair, which has been held in Guangzhou, covers more than 140 countries and regions around the world and attracts more than 50000 talents at home and abroad. In order to create a more attractive and competitive innovation ecology and let the sources of innovation flow fully, Guangzhou has made great efforts to remove the obstacles of scientific and technological innovation system and mechanism, revised and promulgated the regulations of Guangzhou Municipality on scientific and technological innovation, solidified the effective reform measures in recent years in the form of legislation, became a programmatic document of the "1 + 5 + n" scientific and technological innovation laws and policies system, and promoted the "negative list" "Competition instead of evaluation", "investment instead of evaluation" and "ranking first" have been continuously deepened. Regulations of Guangzhou Municipality on scientific and technological innovation Set up a special chapter to emphasize basic research and applied basic research, encourage colleges and universities, scientific research institutions, enterprises, social organizations and scientific and technological personnel to carry out basic research and applied basic research, improve the original innovation ability, optimize the discipline layout and R & D layout, promote the cross integration of disciplines, freely explore unknown scientific problems, discover and explore new knowledge fields, and improve the common base The basic technology supply system will enhance the function of the city as the source of scientific and technological innovation; support enterprises to build R & D institutions and joint laboratories independently or jointly with universities and scientific research institutions to carry out applied basic research facing common problems in the industry. It is the first city school (Institute) joint funding project in China to leverage social capital to invest more than 850 million yuan in basic research. In 2020, Guangzhou's total social Rd expenditure was 77.484 billion yuan, an increase of 9.711 billion yuan over the previous year, a year-on-year increase of 14.3%. The investment intensity of RD expenditure increased from 1.9% in 2013 to 3.10% in 2020, the only first tier city to achieve rapid growth for seven consecutive years. Concentrate on tackling key problems and speed up the tackling of core technologies At present, Guangzhou, which is rapidly moving towards high-level scientific and technological self-reliance and self-improvement, is moving towards the key turning point of switching the driving force of development, improving its technological innovation ability, leading and running in more fields, which is conducive to mastering the initiative of development. Guangzhou actively practices the new national system of tackling key core technologies, deeply implements the R & D plan in key fields, and lays out a new generation of communication and network and artificial intelligence Energy, intelligent networked vehicles, new energy, brain science and brain like research, health care, biomedicine, new materials, marine economy and other nine special projects, developed the world's first 31 inch inkjet printing windable flexible prototype, the world's first manned autopilot aircraft and other innovative products, and made breakthrough progress in tackling a number of "neck" technologies. Filter is the core device of mobile phone RF front-end, which belongs to 35 "necks" combed by science and technology daily One of the technologies. At present, China's RF filters are basically monopolized by foreign giants, with a market share of less than 5%. Civil use basically depends on imports, but the market demand exceeds 50 billion, and the localization process needs to be accelerated. Under the leadership of academician Zhao Yuliang, the National Nanotechnology Innovation Research Institute of Guangdong Guangdong Guangdong Hong Kong Macao Dawan district gathers first-class talents at home and abroad to jointly tackle key problems and overcome technology day and night Technical problems, efforts have been made to break through the blockade of key core technologies, and breakthroughs have been made in the key engineering technologies of 5g SAW filter chips. The 5g filter project takes only 10 months from starting on the ground to running on the production line, laying a solid foundation for fully realizing the independent control of 5g RF filter chips from technology to products, and realizing large-scale manufacturing and industrialization. Constantly enrich the "sunshine", "air" and "water" on which innovation and entrepreneurship activities depend, and build an efficient transformation system for innovation achievements. In 2020, the turnover of technology contracts in the city reached 225.6 billion yuan, jumping to the second place in China, opening up the "medium barrier" for the transformation of scientific and technological achievements In, it fully reflects the abundant source supply of scientific and technological achievements in Guangzhou, the smooth transformation channels, the prosperity of supply and demand, and the acceleration of more scientific research achievements from "bookshelves" to "shelves". The construction of scientific and technological achievements transformation bases around Huagong, Central University and Central University City has accelerated the development of technology market in an all-round way. Cultivate main bodies and lead industrial innovation and development *** The earnest advice of the general secretary has greatly enhanced the development confidence of small and medium-sized enterprises and stimulated the innovation vitality of countless small and medium-sized enterprises. Guangzhou has a beautiful ecological environment, is a happy city suitable for living and working, and is also a "fertile land for innovation" of scientific and technological enterprises After years of development, it has gathered 12000 high-tech enterprises. The number of national scientific and technological small and medium-sized enterprises that have been put on record for three years ranks first in China, and a large number of leading enterprises and "invisible champions" in subdivided industries Competing to emerge, it has become the driving force for high-quality economic and social development. The number of high-tech enterprises with revenue of more than 10 billion yuan, 1 billion yuan and 1.723 billion yuan has reached 20, 256 and 1.723 respectively, increasing by 150%, 175% and 204% respectively since 2015. Over the past two years, mingluo equipment has deeply implemented the instructions and expectations of the general secretary, firmly followed the path of independent innovation, and established a complete set of automobile non-standard intelligent equipment The industry's design and manufacturing standards and the flexibility, refinement and standardization ability of automobile production lines are world leaders, realizing the transformation from "made in China" to "created in China" In the scientific and technological anti epidemic, the production capacity of Daan gene nucleic acid detection kit has been increased to 5 million people per day, with a cumulative sales volume of more than 550 million people, ranking first in China; the daily detection capacity of Jinyu medicine exceeds 1 million tubes, with a cumulative detection capacity of more than 220 million people in China, and the daily detection capacity and cumulative detection capacity of a single agency rank first in the world; the antigen detection product developed and produced by Wanfu biology is our company China's first approved COVID-19 antigen detection reagent. Guangzhou has always enjoyed the reputation of "Millennium Business Capital". Under the tide of digital economy, it has accelerated the opening of the "digital intelligence" engine, enabling traditional industries to glow with new vitality. Vipshop has made concerted efforts to build a world-class e-commerce platform and was successfully selected in fortune in 2020 China's top 500 and 2020 China's top 500 private enterprises list. Perfect diary has ranked first in tmall's cosmetics sales for three consecutive years. Behind the 600 million yuan online sales is the acceleration of big data and cloud technology, which has helped to increase the system throughput by 50 times; mingchuangyou products has become the world's largest comprehensive retail seller of free brands, and the system provided by SAP, the world's top enterprise software supplier, has greatly improved its global procurement and sales Efficiency of supply chain