With the accelerated innovation of Internet, big data, cloud computing, artificial intelligence, blockchain and other technologies, digital economy is becoming a key force to change the global competition pattern, playing an important role in promoting the upgrading of industrial structure and promoting high-quality development of regional economy. In recent years, China's digital economy has achieved leapfrog development with policy support and market promotion, and its scale has steadily expanded. The scale of the digital economy has ranked second in the world for many consecutive years. At the same time, it should be noted that the digital economy has the problem of unbalanced development among regions. The development basis and industrial structure of digital economy vary from place to place, resulting in different quality and level of digital economy development among regions. To some extent, the imbalance of digital economy development among regions can be understood as the different stages of digital economy development. The eastern region vigorously gathers resources by virtue of its strong digital technology application and innovation level, large-scale market, more developed digital industry and other advantages. The digital economy infrastructure is relatively complete, and the development of digital economy has a good foundation; The central region is relatively abundant in land elements and energy resources, but the digital infrastructure is not perfect, and the application and innovation of digital technology are constantly developing; The industrial foundation in the western region is relatively weak, and the application and innovation of digital technology are relatively lagging behind. There is still much room for development in the construction of digital infrastructure. To narrow the development gap of digital economy among regions, each region needs to combine its own conditions, rely on the advantages of local industry, location, resources, policies, etc., take measures according to local conditions, implement precise policies, complement the development weaknesses, explore the development paths of digital economy with different characteristics, and realize the coordinated development of regional digital economy. By building a mechanism of coordinated development and complementary advantages among regions, we will promote industrial transformation and upgrading in all regions and stimulate the potential for economic growth. At the same time, it is necessary to adhere to the concept of system, explore an effective linkage mechanism for the development of digital economy in the eastern, central and western regions, effectively combine the advantages of technology, market and industry in the eastern region with the advantages of resource endowment and environment in the central and western regions, and promote the formation of a new pattern of coordinated regional development. First, strengthen the top-level design and policy guarantee of the digital economy in combination with regional characteristics and advantages. It is necessary to fully identify the resource endowments and realistic industrial bases of different regions, find out the advantages and disadvantages of their respective development, formulate a digital economy development plan with regional characteristics, and constantly release the development potential of regional digital economy; In addition, we should take into account the digital economy and industrial structure of the surrounding regions, plan the positioning and role of different regions in the development of digital economy in an integrated way, take targeted and precise measures, and form a policy system to promote the coordinated development of regional digital economy. We should strengthen policy support in technology, talent, capital, infrastructure and public services, optimize the institutional mechanisms in terms of regulatory, financial support, tax incentives, and network security, and create a good environment for the development of the digital economy. Second, we will strive to improve the level of digital technology innovation and application in the eastern region, and promote the development of digital industries in key areas. The eastern region has a good basic advantage in the development of digital economy. It should take the lead in tackling the key core technologies of digital economy, strengthen the innovation and application of digital technology, build a digital industry cluster, and accelerate the pace of digital society construction. In terms of system guarantee, we should constantly improve the number of